GENOMIC FEATURES, ANTIMICROBIAL SUSCEPTIBILITY, AND EPIDEMIOLOGICAL INSIGHTS INTO BURKHOLDERIA CENOCEPACIA CLONAL COMPLEX 31 ISOLATES FROM BLOODSTREAM INFECTIONS IN INDIA

Genomic features, antimicrobial susceptibility, and epidemiological insights into Burkholderia cenocepacia clonal complex 31 isolates from bloodstream infections in India

IntroductionBurkholderia cepacia complex (Bcc) clonal complex (CC) 31, the predominant lineage causing devastating outbreaks globally, has Back up Gateway been a growing concern of infections in non-cystic fibrosis (NCF) patients in India.B.cenocepacia is very challenging to treat owing to its virulence determinants and antibiotic resistance.Improv

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Downsloping high-frequency hearing loss due to inner ear tricellular tight junction disruption by a novel ILDR1 mutation in the Ig-like domain.

The immunoglobulin (Ig)-like domain containing receptor 1 (ILDR1) gene encodes angulin-2/ILDR1, a recently discovered tight junction protein, which forms tricellular tight junction (tTJ) structures with tricellulin and lipolysis-stimulated lipoprotein receptor (LSR) at tricellular contacts (TCs) in the inner ear.Previously reported recessive mutati

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